Day 4 on Arthur Ashe Stadium was a breeze for top seeds. Caroline Wozniacki, Roger Federer, Vera Zvonareva, Maria Sharapova and Novak Djokovic.

On Louis Armstrong Stadium and Grandstand, Jelena Jankovic, Svetlana Kuznetsova, Robin Soderling and Americans James Blake and Mardy Fish advanced into the 3rd Round.

Thursday was not as sweet for a couple of the men's top seeds. No. 6 Nikolay Davydenko became the highest men's seed to lose so far in the tournament as he fell to Richard Gasquet in straight sets. No. 11 Marin Cilic also made an early exit as he lost to qualifier Kei Nishikori in a match lasting nearly five hours.  On the women's side, No. 9 Agnieszka Radwanska fell to Shuai Peng.

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